Sodium Hydroxide → HCID 21442734, compound

HRID 328616Notes

Reaction equation

[Cl:1][C:2]1[CH:28]=[CH:27][CH:26]=[CH:25][C:3]=1[C:4]([C:6]1[CH:10]=[C:9]([CH2:11][CH3:12])[S:8][C:7]=1[N:13]1[C:17]([CH2:18][Cl:19])=[N:16][C:15]([C:20]([O:22]CC)=[O:21])=[N:14]1)=[O:5].[OH-].[Na+]>>[Cl:1][C:2]1[CH:28]=[CH:27][CH:26]=[CH:25][C:3]=1[C:4]([C:6]1[CH:10]=[C:9]([CH2:11][CH3:12])[S:8][C:7]=1[N:13]1[C:17]([CH2:18][Cl:19])=[N:16][C:15]([C:20]([OH:22])=[O:21])=[N:14]1)=[O:5]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 21442753HCID 21442753, compound

Product 1

HCID 21442734HCID 21442734, compound

Procedure

Hydrolysis of 0.438 g. of ethyl 1-[3-(2-chlorobenzoyl)-5-ethyl-2-thienyl]-5-chloromethyl-1H-1,2,4-triazole-3-carboxylate is hydrolyzed with sodium hydroxide in the same manner as in a) gives 1-[3-(2-chlorobenzoyl)-5-ethyl-2-thienyl]-5-chloromethyl-1H-1,2,4-triazole-3-carboxylic acid as an oily substance. Infra red absorption spectrum (neat): 1735cm-1 (COOH), 1665cm-1 (C=O).

Workup

customHydrolysis of 0.438 g

Sources & evidence

ORD record: ord-9400dacb15814f3280a48b31184fa760
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04017620

Reaction notes

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