Methyl iodide → HCID 178480905, compound

Participants

Reaction Steps

A mixture of 6.6 parts of 1-[β-(p-chlorobenzyloxy)phenethyl]imidazole, 4.2 parts of methyl iodide and 24 parts of acetonitrile is stirred and refluxed for 4 hours. Upon the addition of 80 parts of ether, the quaternary salt is precipitated. It is filtered off and crystallized from a mixture of 24 parts of acetone and 24 parts of diisopropyl ether, yielding 5 parts of 1-[β-(p-chlorobenzyloxy)phenethyl]-3-methylimidazolium iodide; mp. 112° C.

Provenance & Evidence