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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 328890Generated: October 25, 2026

M-Cresol → Toliprolol

https://huagongshe.com/reaction/328890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
Reactant1-(Propan-2-yl)azetidin-3-olHCID 544677—
ProductToliprololHCID 1804781%

Reaction Steps

1-(iso-propyl)-3-azetidinol and m-cresol were reacted in the same manner as in Example 7 to yield 1-(3'-methyl-phenoxy)-3-(iso-propylamino)-2-propanol melting at 80°-82° C. The yield was 81%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04018824
Source datasetuspto-grants-1977_04
ORD IDord-c81255699c284ab691edcfe07c57e867
Source noteuspto-grants-1977_04