HCID 12408770, compound → HCID 21440115, compound

HRID 328946Notes

Reaction equation

HRID 328946 reaction equation
NC1C=C(C=C([N+]([O-])=O)C=1C(=O)C1C=CC=CC=1)C(O)=[O:6].N[C:23]1[CH:24]=[C:25]([CH:29]=[C:30]([N+:41]([O-:43])=[O:42])[C:31]=1[C:32](=[O:40])[C:33]1[CH:38]=[CH:37][C:36]([CH3:39])=[CH:35][CH:34]=1)[C:26]([OH:28])=[O:27]>>[OH:6][C:23]1[CH:24]=[C:25]([CH:29]=[C:30]([N+:41]([O-:43])=[O:42])[C:31]=1[C:32](=[O:40])[C:33]1[CH:38]=[CH:37][C:36]([CH3:39])=[CH:35][CH:34]=1)[C:26]([OH:28])=[O:27]

Participants

3

Reactant 2

HCID 12408770HCID 12408770, compoundHCID 21440201HCID 21440201, compound

Product 1

HCID 21440115HCID 21440115, compound

Procedure

By replacing in Example 1, step A, 3-amino-4benzoyl-5-nitrobenzoic acid with 3-amino-4-(4'-methylbenzoyl)-5-nitrobenzoic acid and following the procedure described, 3-hydroxy-4-(4'-methylbenzoyl)-5-nitrobenzoic acid is obtained as a hemihydrate with a melting point of 249.5°-251° C.

Sources & evidence

ORD record
ord-e7e6840aabca4de6bb5c2fbe1d811cca
Source dataset
uspto-grants-1977_04
Patent number
US04018794

Reaction notes

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