Acetic Acid → HCID 54533504, compound

HRID 328977Notes

Reaction equation

HRID 328977 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:12]=O)[C:6](=[CH:10][CH:11]=1)[C:7]([OH:9])=[O:8].[S:14]1[CH2:20][C:18](=[O:19])[NH:17][C:15]1=[S:16].C(O)(=O)C.C([O-])(=O)C.[Na+]>O>[C:7]([C:6]1[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][C:5]=1[CH:12]=[C:20]1[S:14][C:15](=[S:16])[NH:17][C:18]1=[O:19])([OH:9])=[O:8]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 517045Sodium AcetateHCID 1201546RhodanineHCID 162152102-Formyl-4-methoxybenzoic acid

Product 1

HCID 54533504HCID 54533504, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred hot solution of 4.23 g. (23.5 mM) of 4-methoxyphthalaldehydic acid and 3.13 g. (23.5 mM) of rhodanine in 16.5 ml. of acetic acid is added 6.33 g. (77.2 mM) of anhydrous sodium acetate. The resulting hot solution is refluxed for 0.5 hour, whereupon a solid yellow mass forms. The mixture is cooled, poured into water, to yield 5-(2-carboxy-5-methoxybenzylidene)rhodanine.

Workup

  1. temperatureThe resulting hot solution is refluxed for 0.5 hour, whereupon a solid yellow mass forms
  2. temperatureThe mixture is cooled

Sources & evidence

ORD record
ord-11c834b1b30f44a282f1141b055cc50f
Source dataset
uspto-grants-1977_04
Patent number
US04018891

Reaction notes

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