反应详情

To a hot stirred solution of 2-carboxyacetophenone (1.91 g., 11.65 mM) and 1.57 g. (11.75 mM) of rhodanine in 8 ml. of acetic acid is added 3.12 g. (38.1 mM) of sodium acetate. The solution is refluxed for 3.5 hours, cooled, and poured into water, whereupon a gum forms. The gum crystallizes and is collected and recrystallized from methanol to give 5-(2-carboxy-α-methylbenzylidene) rhodanine as yellow-brown crystals, m.p. 193°-195°.

1. temperatureThe solution is refluxed for 3.5 hours
2. temperaturecooled
3. customThe gum crystallizes
4. customis collected
5. customrecrystallized from methanol