Acetic Acid → HCID 54339098, compound

HRID 328989Notes

Reaction equation

HRID 328989 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:5]([C:6]([OH:8])=[O:7])[C:4]=1[CH:12]=O.[S:14]1[CH2:20][C:18](=[O:19])[NH:17][C:15]1=[S:16].C(O)(=O)C.C([O-])(=O)C.[Na+]>O>[C:6]([C:5]1[CH:9]=[CH:10][CH:11]=[C:3]([O:2][CH3:1])[C:4]=1[CH:12]=[C:20]1[S:14][C:15](=[S:16])[NH:17][C:18]1=[O:19])([OH:8])=[O:7]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 517045Sodium AcetateHCID 1201546RhodanineHCID 127303562-Formyl-3-methoxybenzoic acid

Product 1

HCID 54339098HCID 54339098, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred hot solution of 0.45 g. (2.50 mM) of 3-methoxyphthalaldehydic acid and 0.34 g. (2.50 mM) rhodanine in 3 ml. of acetic acid is added 0.68 g. (8.2 mM) of anhydrous sodium acetate. The resulting solution is refluxed 1.5 hours, cooled, and poured into 40 ml. of water to give a yellow gum which slowly solidifies to a yellow solid. The solid is collected, washed with water, and air-dried to give 5-(2-carboxy-6-methoxybenzylidene)rhodanine.

Workup

  1. temperatureThe resulting solution is refluxed 1.5 hours
  2. temperaturecooled
  3. additionpoured into 40 ml
  4. customThe solid is collected
  5. washwashed with water
  6. customair-dried

Sources & evidence

ORD record
ord-89a1da70cc19478a8165db6a8691c4f2
Source dataset
uspto-grants-1977_04
Patent number
US04018891

Reaction notes

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