HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorohydroxy benzophenone → 5-Chloro-2-Hydroxy-3-Iodobenzophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorohydroxy benzophenone | HCID 6799 | — |
| Reactant | Iodine chloride | HCID 24640 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Chloro-2-Hydroxy-3-Iodobenzophenone | HCID 20361862 | — |
Reaction Steps
Add 5-chloro-2-hydroxybenzophenone (23.2 g., 0.1 mole) to acetic acid (150 ml.) and sodium acetate (9.3 g., 0.11 mole). Treat the mixture with iodine monochloride (16.5 g., 0.1 mole) and warm in a bath at 70°-85° for one hour. Cool and add 20 ml. of sodium bisulfite solution and then more water. After stirring for five minutes, collect and dry the title compound; m.p. 110°-111° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04018893 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-d073d9e863944d788a7b2ccb6ed78964 |
| Source note | uspto-grants-1977_04 |