1-(5-Ethoxy-2-nitrophenyl)piperidine → 4-Ethoxy-2-(piperidin-1-yl)aniline

Beteiligte Stoffe

Reaktionsschritte

Using a procedure similar to Example 3, step (c), 1-(5-ethoxy-2-nitro-phenyl)-piperidine (78 mg, 0.31 mmol, as prepared in the previous step) was stirred with 42 mg of 5% Pd—C under H2 to afford 64 mg (94%) of the title compound which was used immediately without further purification. Mass spectrum (ESI, m/z): Calcd. for C13H20N2O, 221.1 (M+H), found 221.1.

Herkunft & Nachweise