Thionyl Chloride → HCID 86734598, compound

HRID 329025Notes

Reaction equation

HRID 329025 reaction equation
[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][C:13]([OH:15])=O)=[CH:8][CH:7]=2)[CH2:5][CH2:4][N:3]=[CH:2]1.S(Cl)([Cl:18])=O>C1C=CC=CC=1>[ClH:18].[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][C:13]([Cl:18])=[O:15])=[CH:8][CH:7]=2)[CH2:5][CH2:4][N:3]=[CH:2]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 68117104HCID 68117104, compound

Product 1

HCID 86734598HCID 86734598, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

10 g of 4-(2-Imidazolinyl)-phenylacetic acid were stirred for 5 hours at 55° C with a mixture of 150 ml of benzene and 90 ml of thionyl chloride. The reaction mixture was then cooled, filtered with suction, washed with benzene and diethyl ether and dried under reduced pressure. 11 g of 4-(2-Imidazolinyl)-phenylacetic acid chloride-hydrochloride were obtained.

Workup

  1. temperatureThe reaction mixture was then cooled
  2. filtrationfiltered with suction
  3. washwashed with benzene and diethyl ether
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-be4d8f1d817e4afea11c3912ffe557ed
Source dataset
uspto-grants-1977_04
Patent number
US04018933

Reaction notes

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