1-(2-Methyl-6-nitrophenyl)piperidine → 3-Methyl-2-(1-piperidinyl)aniline

Beteiligte Stoffe

Reaktionsschritte

Using a procedure similar to Example 3, step (c), 1-(2-methyl-6-nitro-phenyl)-piperidine (74 mg, 0.38 mmol, as prepared in the previous step) was stirred with 5% Pd—C (50 mg) under H2 to afford 66 mg (91%) of the title compound as an oil. Mass spectrum (ESI, m/z): Calcd. for C12H18N2, 191.1 (M+H), found 191.1.

Herkunft & Nachweise