HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cysteamine Hydrochloride | HCID 9082 | — |
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | Picrate | HCID 4432340 | — |
| Reactant | HCID 178479151 | HCID 178479151 | — |
| Reactant | HCID 178511470 | HCID 178511470 | — |
| Product | N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea | HCID 178486118 | — |
Reaction Steps
Reaction of 2-amino-4-hydroxymethylimidazole hydrochloride (which is obtained by treating the picrate salt with hydrochloric acid) with cysteamine hydrochloride and reaction of the resulting 2-amino-4-[(2-aminoethyl)-thiomethyl]imidazole with methyl isothiocyanate by the methods of Example 1 gives N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04018931 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-af333b7906ac4724816e21d2af24bb2d |
| Source note | uspto-grants-1977_04 |