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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 329074Generated: October 30, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thiourea

https://huagongshe.com/reaction/329074

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-[(2-Aminoethyl)thiomethyl]pyrimidineHCID 20242485—
ProductN-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thioureaHCID 20557794—

Reaction Steps

By the procedure of Example 18, 2-[(2-aminoethyl)-thiomethyl]pyrimidine is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 give N-[2-(2-pyrimidylmethlthio)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04018931
Source datasetuspto-grants-1977_04
ORD IDord-da55414c5b324891bbb5fc3d35a388b3
Source noteuspto-grants-1977_04