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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 329094Generated: October 30, 2026

Hydrogen Bromide → 5-((2-Aminoethyl)thiomethyl)thiazole dihydrobromide

https://huagongshe.com/reaction/329094

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantMethanolHCID 887—
ReactantCysteamine HydrochlorideHCID 9082—
Reactant5-ThiazolylmethanolHCID 2763216—
Product5-((2-Aminoethyl)thiomethyl)thiazole dihydrobromideHCID 20557845—

Reaction Steps

The reaction of 5-hydroxymethylthiazole (2.01 g.) with cysteamine hydrochloride (1.99 g.) in aqueous hydrobromic acid by the method described in Example 1(i)(a) gave 5-[(2-aminoethyl)thiomethyl]thiazole dihydrobromide (4.85 g.), m.p. 191°-194° (from methanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04018931
Source datasetuspto-grants-1977_04
ORD IDord-accc9d47a2574790a0f3165a5ada82d1
Source noteuspto-grants-1977_04