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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 329107Generated: October 31, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thiourea

https://huagongshe.com/reaction/329107

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant4-Methyl-5-[(2-aminoethyl)thiomethyl]oxazoleHCID 12543863—
ProductN-benzoyl-N'-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thioureaHCID 20557859—

Reaction Steps

5-[(2-Aminoethyl)thiomethyl]-4-methyloxazole is reacted with benzoyl isothiocyanate by the procedure of Example 18 to give N-benzoyl-N'-[2-((4-methyl-5-oxazolyl)-methylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04018931
Source datasetuspto-grants-1977_04
ORD IDord-4046b3feef1442a1904856caa91b80cd
Source noteuspto-grants-1977_04