(2-Isothiocyanatoethyl)dimethylamine → N-(2-Dimethylaminoethyl)-N'-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thiourea

HRID 329109Notes

Reaction equation

HRID 329109 reaction equation
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[O:10][CH:9]=[N:8][C:7]=1[CH3:11].[CH3:12][N:13]([CH3:19])[CH2:14][CH2:15][N:16]=[C:17]=[S:18]>>[CH3:12][N:13]([CH3:19])[CH2:14][CH2:15][NH:16][C:17]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[O:10][CH:9]=[N:8][C:7]=1[CH3:11])=[S:18]

Participants

3

Reactant 2

HCID 3853726(2-Isothiocyanatoethyl)dimethylamineHCID 125438634-Methyl-5-[(2-aminoethyl)thiomethyl]oxazole

Product 1

HCID 20557577N-(2-Dimethylaminoethyl)-N'-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thiourea

Procedure

5-[(2-Aminoethyl)thiomethyl]-4-methyloxazole is reacted with 2-dimethylaminoethyl isothiocyanate by the procedure of Example 1 to give the title compound.

Sources & evidence

ORD record
ord-ae87de17185f405081e8160df17e1643
Source dataset
uspto-grants-1977_04
Patent number
US04018931

Reaction notes

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