HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-Methyl-N'-[2-(2-thiazolylmethylamino)ethyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 2-(Chloromethyl)-1,3-thiazole | HCID 14090864 | — |
| Reactant | N-(2-thiazolylmethyl)ethylenediamine | HCID 17944882 | — |
| Product | N-Methyl-N'-[2-(2-thiazolylmethylamino)ethyl]urea | HCID 20557949 | — |
Reaction Steps
N-(2-Thiazolylmethyl)ethylenediamine, prepared by reacting ethylenediamine with 2-chloromethylthiazole by the procedure of Example 40, is reacted with methyl isocyanate by the procedure of Example 24 to give, after concentrating and separating by column chromatography, the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04018931 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-306d0135d0694b778acdfaa42317621d |
| Source note | uspto-grants-1977_04 |