HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-Methyl-N'-[2-(3-isothiazolylmethylamino)ethyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 3-(bromomethyl)Isothiazole | HCID 13037598 | — |
| Reactant | N-(3-isothiazolylmethyl)ethylenediamine | HCID 20557777 | — |
| Product | N-Methyl-N'-[2-(3-isothiazolylmethylamino)ethyl]urea | HCID 20557581 | — |
Reaction Steps
N-(3-Isothiazolylmethyl)ethylenediamine, prepared by reacting ethylenediamine with 3-bromomethylisothiazole by the procedure of Example 40(a), is reacted with methyl isocyanate by the procedure of Example 24 to give, after concenrating and separating by column chromatography, the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04018931 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-2431cb88d58448ea9b04aa1790e12e6c |
| Source note | uspto-grants-1977_04 |