4-Ethoxyaniline → HCID 68122063, compound

Participants

Reaction Steps

To a solution of 1-acetoxy-2-bromoquinolizinium bromide (30.0 g., 0.09 mole) in isopropanol (600 ml.) was added p-phenetidin (24.0 g., 0.18 mole). The stirred mixture was boiled under reflux for 4 hours, during which time solid had precipitated from solution. The cooled mixture was filtered and washed with ether. The product as yellow needles weighed 37.0 g. (97%). Recrystallization from alcohol-ether provided yellow needles which melted at 161°-162°.

Provenance & Evidence