Formaldehyde → HCID 178463053, compound

Participants

Reaction Steps

28.7 g. of 3,6-dimethyl-1-ethyl-1H-pyrazolo[3,4-b]pyridin-4-ol (0.15 mol.), 6.75 g. of paraformaldehyde (0.22 mol.) and 13.5 g. of dimethylamine hydrochloride (0.165 mol.) suspended in 400 ml. dimethylformamide is reacted and worked up according to the procedure of Example 6 to obtain 5-[(dimethylamino)methyl]-3,6-dimethyl-1-ethyl-1H-pyrazolo[3,4-b]pyridin-4-ol, hydrochloride (1:1) yield 30.3 g. (71%), m.p. 242°-245°.

Provenance & Evidence