Isopropylamine → Oxazole, 4,5-diphenyl-2-((isopropylamino)methyl)-, monohydrochloride

HRID 329208Notes

Reaction equation

HRID 329208 reaction equation
[Cl:1][CH2:2][C:3]1[O:4][C:5]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1.[CH:20]([NH2:23])([CH3:22])[CH3:21]>C1C=CC=CC=1>[ClH:1].[CH:20]([NH:23][CH2:2][C:3]1[O:4][C:5]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1)([CH3:22])[CH3:21]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 12413149HCID 12413149, compound

Product 1

HCID 214407Oxazole, 4,5-diphenyl-2-((isopropylamino)methyl)-, monohydrochloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 8 g. 2-chloromethyl-4,5-diphenyloxazole (prepared as described in Example 1 a), 8g. isopropylamine and 50 ml. anhydrous benzene was kept in a stoppered flask for 48 hours at room temperature.

Workup

  1. additionA mixture of 8 g

Sources & evidence

ORD record
ord-dcd84dec06eb4c74b3a2e3f674da7fbb
Source dataset
uspto-grants-1977_04
Patent number
US04020082

Reaction notes

Loading…