2-Aminothiophenol → HCID 68123792, compound

HRID 329252Notes

Reaction equation

HRID 329252 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][C:12]=1[CH:13]=O>>[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][C:12]=1[C:13]1[S:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[N:1]=1

Participants

3

Reactant 2

HCID 87132-AminothiophenolHCID 667262,5-Dimethoxybenzaldehyde

Product 1

HCID 68123792HCID 68123792, compound

Procedure

2-Aminothiophenol (6.3 g., 0.05 mole) and 8.3 g (0.05 mole) of 2,5-dimethoxybenzaldehyde were combined and mixed thoroughly. After a few minutes the mixture evolved heat, became cloudy, and slowly crystallized. The mixture was then warmed for a few minutes to complete the reaction. The product was then recrystallized from ethanol yielding 8.0 g (59%), mp. 96°-99°.

Workup

  1. additionmixed thoroughly
  2. temperatureAfter a few minutes the mixture evolved heat
  3. customslowly crystallized
  4. temperatureThe mixture was then warmed for a few minutes
  5. customthe reaction
  6. customThe product was then recrystallized from ethanol yielding 8.0 g (59%), mp. 96°-99°

Sources & evidence

ORD record
ord-55321640a39644f1bdb34400c5dee75d
Source dataset
uspto-grants-1977_04
Patent number
US04020165

Reaction notes

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