Benzene → HCID 86734703, compound

Participants

Reaction Steps

To a solution of 800 mg of 1-chloro-2,3,6-trideoxy-3-trifluoroacetamido-4-trifluoroacetoxy-alpha-L-lyxohexopyranose (I)* in 25 ml of a 4:1 (by volume) mixture of benzene and dioxane there were added 500 mg of Hg(CN)2. The resulting suspension was heated under reflux for 3 1/2 hours. After cooling, the reaction mixture was filtered to give a clear solution, which was then evaporated to a residue. The residue was extracted with benzene and, upon evaporation of the benzene solution, there were obtained 650 mg of 1,2,3,6-tetradeoxy-3-trifluoroacetamido-4-trifluoroacetoxy-L-lyxo-hex-1-enopyranose (II) in crystalline form melting at 73°-74° C.

Provenance & Evidence