反应详情

34.4 g (0.11 mol) of 2-bromo-1-(3,5-di-tert.butyl-4-hydroxyphenyl)-ethanone from Example 1(a) and 13.8 g (0.11 mol) of 1-amino-2-thioxo-5-imidazolidinone from step (a) were heated at 90° C. for 30 minutes in 300 ml of glacial acelic acid. After cooling, the precipitate was filtered off and washed with 250 ml of ethyl acetate, and the crystals were dried in vacuo over phosphorus pentoxide.

1. temperatureAfter cooling
2. filtrationthe precipitate was filtered off
3. washwashed with 250 ml of ethyl acetate
4. dry with materialthe crystals were dried in vacuo over phosphorus pentoxide