Cyclohex-2-ene-1,2-dicarboxylic acid → 3a,4,5,6-Tetrahydro-2-benzofuran-1,3-dione

Participants

Reaction Steps

A stirred solution of 5.0 grams (0.029 mole) of cyclohexene-2,3-dicarboxylic acid in 30 ml of acetic anhydride and 100 ml of acetic acid was heated under reflux for four hours. The reaction mixture was concentrated under reduced pressure to a residual oil. The oil was washed with petroleum ether and evacuated under high vacuum to yield 2.2 grams of 2,3,4,5-tetrahydrophthalic anhydride as a semi-solid.

Provenance & Evidence