HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sulfometuron-methyl | HCID 52997 | — |
| Reactant | O-ethylhydroxylamine hydrochloride | HCID 76850 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide | HCID 19871558 | — |
Reaction Steps
To 2.9 g of trimethylaluminum in 100 ml of methylene chloride is added 2.0 g of ethoxyamine hydrochloride with stirring at ambient temperature. To this mixture is added 3.0 g of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide and the solution is refluxed for 18 hours. The reaction mixture is treated with aqueous hydrochloric acid and the resulting precipitated product is purified by chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892946 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-a3ef8abf81d14e7cb104d6a293d44aef |
| Source note | uspto-grants-1990_01 |