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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 329797Generated: October 25, 2026

N-Acetyl-L-phenylalanine → 2-Acetamidocinnamic acid

https://huagongshe.com/reaction/329797

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Acetyl-L-phenylalanineHCID 74839—
Reactant4-benzylidene-2-methyl-4H-oxazol-5-oneHCID 94946—
SolventWaterHCID 962—
Product2-Acetamidocinnamic acidHCID 53423741—

Reaction Steps

The invention relates to a process for the preparation of N-acetylphenylalanine by opening the ring of 2-methyl-4-benzylidene-1,3-oxazolin-5-one with water to give 2-acetaminocinnamic acid and subsequent catalytic hydrogenation of the latter.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04892971
Source datasetuspto-grants-1990_01
ORD IDord-0b0e45101be14b5a829e7f4724fe9210
Source noteuspto-grants-1990_01