2,3-Dichlorobenzaldehyde → HCID 19871256, compound

Participants

Reaction Steps

A mixture of 2,3-dichlorobenzaldehyde, 2-[4-(4,4'-dichlorobenzhydryl)-1-piperazinyl]ethyl acetoacetate and methyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-[4-(4,4'-dichlorobenzhydryl)-1-piperazinyl]ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate as a light yellow powder, m.p. 104°-107° C. (sintering). Yield 43.2%. IR(KBr)cm-1 : 3340, 1695. NMR(CDCl3) δ: 2.27(6H,s, ##STR25## 3.57(3H,s,COOCH3), 4.12(2H,t,J=6,--COOCH2CH2 --), 4.18(1H,s,>N--CH<), 5.43(1H,s,C(4) --H), 5.70(1H,broad s, NH).

Provenance & Evidence