Isopropanol → HCID 19871234, compound

Participants

Reaction Steps

A mixture of m-nitrobenzaldehyde, 2-(4-benzhydrylhomopiperazin-1-yl)ethyl acetoacetate and methyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-(4-benzhydrylhomopiperazin-1-yl)-ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate as a light yellow powder, m.p. 60°-63° C. (sintering). Yield 31.7%. IR(KBr)cm-1 : 3330, 1690. NMR(CDCl3) δ: 2.33(6H,s, ##STR26## 3.60(3H,s), 4.12(2H,t,J=6), 4.57(1H,s,>N--CH<), 5.10(1H,s,C(4) --H), 5.92(1H,s,NH).

Provenance & Evidence