3-Nitrobenzaldehyde → HCID 19871226, compound

Participants

Reaction Steps

A mixture of m-nitrobenzaldehyde, 2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl acetoacetate and methyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate as a light yellow powder, m.p. 65°-68° C. (sintering). Yield 29.0%. IR(Nujol)cm-1 : 3300. NMR(CDCl3) δ: 2.34(3H,s, ##STR29## 2.36(3H,s, ##STR30## 3.63(3H,s,COOCH3), 4.21(2H,t,J=6,--COOCH2CH2 --), 5.12(1H,s,C(4) --H), 5.89(1H,s,NH).

Provenance & Evidence