HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrobenzaldehyde → HCID 15611329, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrobenzaldehyde | HCID 7449 | — |
| Reactant | Methyl 3-aminocrotonate | HCID 643918 | — |
| Reactant | 2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl 3-oxobutanoate | HCID 19870764 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 15611329 | HCID 15611329 | 55.6% |
Reaction Steps
A mixture of m-nitrobenzaldehyde, 2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl acetoacetate and methyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-[4-(2-methoxyphenyl)-1-piperazinyl]-ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate as a light yellow powder, m.p. 58° C. (sintering). Yield 55.6%. NMR(CDCl3) δ: 2.34(6H,s, ##STR32## 3.63(3H,s,OCH3), 3.83(3H,s,OCH3), 4.21(2H,t,J=6, --COOCH2CH2 --), 5.14(1H,s,C(4) --H), 6.60(1H,s,NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892875 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-0d9cce0aa5724bfcbf5e865c1c2521e4 |
| Source note | uspto-grants-1990_01 |