HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorobenzaldehyde → HCID 19871211, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorobenzaldehyde | HCID 11477 | — |
| Reactant | 2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- | HCID 643756 | — |
| Reactant | Butanoic acid, 3-oxo-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl ester | HCID 11740518 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 19871211 | HCID 19871211 | 43.3% |
Reaction Steps
A mixture of m-chlorobenzaldehyde, 2-(4-benzhydryl-1-piperazinyl)ethyl acetoacetate and ethyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-(4-benzhydryl-1-piperazinyl)ethyl ethyl 4-(3-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate as a light yellow powder, m.p. 72°-75° C. (sintering). Yield 43.3%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892875 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-559e93dd396d417f970cc5bea0fbee40 |
| Source note | uspto-grants-1990_01 |