HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrobenzaldehyde → HCID 19871199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrobenzaldehyde | HCID 7449 | — |
| Reactant | Butanoic acid, 3-oxo-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl ester | HCID 11740518 | — |
| Reactant | HCID 18318308 | HCID 18318308 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 19871199 | HCID 19871199 | 19.5% |
Reaction Steps
A mixture of m-nitrobenzaldehyde, 2-(4-benzhydryl-1-piperazinyl)ethyl acetoacetate and 2-methoxyethyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-(4-benzhydryl-1-piperazinyl)ethyl 2-methoxyethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate as a light yellow powder, m.p. 62°-66° C. (sintering). Yield 19.5%. IR(Nujol)cm-1 : 3300, 1685, 1675. NMR(CDCl3) δ: 2.33(6H,s, ##STR39## 2.5(2H,t,J=6,--CH2CH2N>), 3.29(3H, s,OCH3), 3.49(2H,t,J=4.5,--CH2CH2O--), 5.08(1H,s,C(4) --H), 5.77(1H,broad s, NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892875 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-1d6c5a4fcb2f474fbd630aab5ba9cec9 |
| Source note | uspto-grants-1990_01 |