3-Methoxybenzaldehyde → HCID 19871269, compound

Participants

Reaction Steps

A mixture of m-anisaldehyde, 2-[4-(4,4'-dimethylbenzhydryl)-1-piperazinyl]ethyl acetoacetate and ethyl 3-aminocrotonate was worked up in isopropyl alcohol in the same manner as Example 1 to give 2-[4-(4,4'-dimethylbenzhydryl)-1-piperazinyl]ethyl ethyl 4-(3-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate as a colorless powder, m.p. 75°-78° C. (sintering). Yield 42.2%. IR(Nujol)cm-1 : 3330, 1690. NMR(CDCl3) δ: 1.18(3H,t, J=7,--CH2CH3), 2.25(6H,s, ##STR46## 2.27(3H,s, ##STR47## 2.29(3H,s, ##STR48## 3.68(3H,s,--OCH3), 4.05(2H,q,--CH2CH3), 4.09(1H,s,>N--CH<), 4.14(2H,t,J=6,--COOCH2CH2 --), 4.96(1H, s,C(4) --H), 5.62(1H,broad s, NH).

Provenance & Evidence