HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 2-(2,4-Dichlorobenzoyl)-2-(2,4-dichlorophenyl)oxirane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Urea, (nitrosomethyl)- | HCID 104823 | — |
| Reactant | 1,2-Bis(2,4-dichlorophenyl)ethane-1,2-dione | HCID 13391683 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-(2,4-Dichlorobenzoyl)-2-(2,4-dichlorophenyl)oxirane | HCID 19870083 | — |
Reaction Steps
With cooling and stirring, an ethereal diazomethane solution prepared from 3.1 g of nitrosomethylurea and aqueous sodium hydroxide solution in ether is added dropwise to a solution of 3.4 g of 2,2',4,4'-tetrachlorobenzil in 50 ml of dioxane. When the dropwise addition is complete, stirring is continued for 16 hours at room temperature, and the reaction mixture is then concentrated to dryness. The residual oil is crude 2-(2,4-dichlorobenzoyl)-2-(2,4-dichlorophenyl)oxirane which is purified by high vacuum distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04894083 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-4f354c660f6648798de6101459753803 |
| Source note | uspto-grants-1990_01 |