HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13059516, compound → 2-[2-(4-Dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-3-nitropyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13059516 | HCID 13059516 | — |
| Reactant | 2-(4-Dimethylaminomethyl-2-pyridylmethylthio)ethylamine | HCID 13277327 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[2-(4-Dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-3-nitropyrrole | HCID 14771356 | 15% |
Reaction Steps
A solution of 2-(4-dimethylaminomethyl-2-pyridylmethylthio)ethylamine (0.325 g) and 2-methylsulphinyl-3-nitropyrrole (0.25 g) was refluxed in ethanol (12 ml) over 6 days. The solution was evaporated to dryness and the residue was chromatographed on silica gel eluted with 10% methanol/chloroform to give 2-[2-(4-dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-3-nitropyrrole (0.072 g) as a yellow solid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04894372 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-5eade020f2014fb68caf8b163f99b3fc |
| Source note | uspto-grants-1990_01 |