Bromine → 1-Bromo-4-(2,4-dichlorophenyl)-3,3-dimethyl-2-butanone

HRID 329947Notes

Reaction equation

HRID 329947 reaction equation
[Br:1]Br.[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[CH2:11][C:12]([CH3:17])([CH3:16])[C:13](=[O:15])[CH3:14]>C(Cl)(Cl)Cl>[Br:1][CH2:14][C:13](=[O:15])[C:12]([CH3:17])([CH3:16])[CH2:11][C:5]1[CH:6]=[CH:7][C:8]([Cl:10])=[CH:9][C:4]=1[Cl:3]

Participants

4

Reactant 2

HCID 24408BromineHCID 132100464-(2,4-Dichlorophenyl)-3,3-dimethylbutan-2-one

Product 1

HCID 133403811-Bromo-4-(2,4-dichlorophenyl)-3,3-dimethyl-2-butanoneYield 100.1%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

13.4 ml (0.26 mole) of bromine are slowly added dropwise to a solution of 64.5 g (0.26 mole) of 4-(2,4-dichlorophenyl)-3,3-dimethyl-2-butanone in 600 ml of chloroform at room temperature. The reaction solution is subsequently stirred at room temperature for 1 hour. It is then concentrated by distilling off the solvent. 84.3 g (100% of theory) of crude 1-bromo-4-(2,4-dichlorophenyl)-3,3-dimethyl-2-butanone are obtained as an oil, which is further reacted directly. ##STR15##

Workup

  1. concentrationIt is then concentrated
  2. distillationby distilling off the solvent

Sources & evidence

ORD record
ord-705f38a087b24274bccdd174d2be3435
Source dataset
uspto-grants-1990_01
Patent number
US04894382

Reaction notes

Loading…