HuagongsheHuagongshe Chemistry Print Report · For research reference only
Deferiprone → ZINC 3-hydroxy-1,2-dimethylpyrid-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Deferiprone | HCID 2972 | — |
| Reactant | ZINC 1-ethyl-3-hydroxypyrid-2-one | HCID 70373874 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ZINC 3-hydroxy-1,2-dimethylpyrid-4-one | HCID 70373691 | — |
Reaction Steps
The procedure described under (A) is followed with 3-hydroxy-1,2-dimethylpyrid-4-one in place of 1-ethyl-3-hydroxypyrid-2-one to give the neutral 2:1 complex from ethanol as a white crystalline solid in essentially quantitative yield, m.p. 190° C. (with decomposition); νmax 1655, 1612 cm-1 ; δ(d6DMSO); 7.53 (d, 1H), 6.20 (d, 1H), 3.70 (s, 3H), 2.33 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04894455 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-75c709617744441185b11998ecb3a51b |
| Source note | uspto-grants-1990_01 |