反应详情

A mixture of ethyl 2-(2,4,5-trifluoro-3-methylbenzoyl)acetate (5.02 g), ethyl orthoformate (4.29 g) and acetic anhydride (4.93 g) was stirred at 130° to 135° C. for 5 hours and then concentrated under reduced pressure to give the title compound (6.05 g) as red oil.

1. concentrationconcentrated under reduced pressure