HuagongsheHuagongshe Chemistry Print Report · For research reference only
D-Norvaline → N-Cbz-norvaline amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | D-Norvaline | HCID 439575 | — |
| Reactant | Z-D-Nva-OH | HCID 10106192 | — |
| Reactant | HCID 178427886 | HCID 178427886 | — |
| Product | N-Cbz-norvaline amide | HCID 86739099 | — |
Reaction Steps
N-Benzyloxycarbonyl-D-norvaline (0.1 mole), prepared from commercial D-norvaline by the procedure of Example 19, is reacted with cis/trans 2,2,4,4-tetramethyl-3-hydroxycyclobutylamine by the method of Example 20, Part A, to provide the N-Cbz-norvaline amide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04894464 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-dc6371ae405e4582adb97cb687340f62 |
| Source note | uspto-grants-1990_01 |