HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydrazinopyridine → ethyl 5-amino-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Reactant | 2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester | HCID 78943 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl 5-amino-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylate | HCID 742041 | — |
Reaction Steps
Ethyl(ethoxymethylene)cyanoacetate, 19.5 g, was added in one portion to a solution of 2-hydrazinopyridine, 12.5 g, in 100 mL of absolute ethanol. The reaction was then heated at reflux for 21/2 hours and cooled. The solid which formed was collected by filtration and washed with absolute ethanol. After air-drying, the product weighed 22.6 g and melted at 92°-93° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04895590 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-3034be2087654256808d607274b8ef6e |
| Source note | uspto-grants-1990_01 |