Thionyl Chloride → 4-Butoxybenzoyl chloride

HRID 330390Notes

Reaction equation

HRID 330390 reaction equation
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10](O)=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4].S(Cl)([Cl:17])=O>>[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([Cl:17])=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 729714-Butoxybenzoic acid

Product 1

HCID 1185614-Butoxybenzoyl chloride

Procedure

A solution of 5 g of para-n-butoxy benzoic acid is refluxed for 2 hours in 8 ml of thionyl chloride. The thionyl chloride is then distilled, followed by distillation under reduced pressure and under a dry nitrogen stream of the expected acid chloride. In this way para-n-butoxy benzoic acid chloride of the following formula is obtained: ##STR36##

Workup

  1. distillationThe thionyl chloride is then distilled
  2. distillationfollowed by distillation under reduced pressure and under a dry nitrogen stream of the expected acid chloride

Sources & evidence

ORD record
ord-ba849351ad454b269dbde34b6c615cce
Source dataset
uspto-grants-1990_01
Patent number
US04895986

Reaction notes

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