Isopropylamine → HCID 19869536, compound

HRID 330407Notes

Reaction equation

HRID 330407 reaction equation
OC1C=CC(CC(CC2C=CC(O)=CC=2)=O)=CC=1.BrCCBr.BrCCC1C=C(C(=O)C)C=[CH:28][C:27]=1[O:35][C:36]1[CH:41]=[CH:40][C:39]([C:42](=[O:44])[CH3:43])=[CH:38][C:37]=1CCBr.[CH:48]([NH2:51])([CH3:50])[CH3:49]>>[C:42]([C:39]1[CH:38]=[CH:37][C:36]([O:35][CH2:27][CH2:28][NH:51][CH:48]([CH3:50])[CH3:49])=[CH:41][CH:40]=1)(=[O:44])[CH3:43]

Participants

5

Reactant 4

HCID 6363IsopropylamineHCID 78391,2-DibromoethaneHCID 641303HCID 641303, compoundHCID 57228903HCID 57228903, compound

Product 1

HCID 19869536HCID 19869536, compound

Procedure

4-Hydroxyphenylmethyl ketone is reacted with 1,2-dibromoethane in the presence of base. The product of that reaction, 2-bromoethyl-4-acetylphenyl ether is then reacted with isopropylamine as in Preparation 26 to give the title compound.

Sources & evidence

ORD record
ord-8a95dd33ae844602b0eeb03acf1dfeda
Source dataset
uspto-grants-1990_01
Patent number
US04895840

Reaction notes

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