N-bromobutanimide → HCID 53696022, compound

Participants

Reaction Steps

To a suspension of 0.5 g of N-(2-difluoromethoxybenzyl) sulfonyl-N'-(4,6-dimethoxy-2-pyrimidinyl)thiourea in 20 ml of methanol is added 0.2 g of N-bromosuccinimide with stirring under ice cooling. After stirring for 30 minutes at the same temperature and further for an hour at room temperature, the crystals are collected by filtration, washed with methanol, and recrystallized from acetonitrile to give 0.3 g of the title compound as white crystals.

Provenance & Evidence