Cyclopropylamine → Cyclopropyl-[2-(2,3-difluorophenyl)ethyl]amine
Reaction equation
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][C:10](O)=O.[CH:13]1([NH2:16])[CH2:15][CH2:14]1>>[CH:13]1([NH:16][CH2:10][CH2:9][C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([F:8])[C:2]=2[F:1])[CH2:15][CH2:14]1Participants
3
Procedure
Synthesized according to typical procedures C and D from (2,3-difluorophenyl)-acetic acid and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-8e4d37f722554875b78591c84c8a236d
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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