HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → N-[5-(2,4-dioxothiazolidin-5-yl)methyl-2-hydroxyphenyl]-2-(4-dimethylaminophenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-N,N-dimethylaminophenylacetic acid | HCID 152203 | — |
| Reactant | 5-(3-Amino-4-hydroxybenzyl)-2,4-dioxothiazolidine | HCID 10490108 | — |
| Reactant | 2-(4-(Dimethylamino)phenyl)acetyl chloride | HCID 14723505 | — |
| Product | N-[5-(2,4-dioxothiazolidin-5-yl)methyl-2-hydroxyphenyl]-2-(4-dimethylaminophenyl)acetamide | HCID 10787103 | — |
Reaction Steps
5-(3-amino-4-hydroxybenzyl)-2,4-dioxothiazolidine and 4-(N,N-dimethylamino)phenylacetyl chloride, prepared from 4-(N,N-dimethylamino)phenylacetic acid and oxalyl chloride, are treated in the same manner as described in Example 5-(1) to give N-[5-(2,4-dioxothiazolidin-5-yl)methyl-2-hydroxyphenyl]-2-(4-dimethylaminophenyl)acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04897393 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-55b44d8767cd4a2981c4cfecaa5ec080 |
| Source note | uspto-grants-1990_01 |