1,3-Propanediamine → N-(3-aminopropyl)-pyrrole

HRID 330493Notes

Reaction equation

HRID 330493 reaction equation
[H][H].[NH2:3][CH2:4][CH2:5][CH2:6][NH2:7].[CH2:8]1[CH2:13]CC[CH2:10][CH2:9]1>>[N:3]1([CH2:4][CH2:5][CH2:6][NH2:7])[CH:10]=[CH:9][CH:8]=[CH:13]1

Participants

4

Reactant 3

HCID 4281,3-PropanediamineHCID 8078CyclohexaneHCID 178418361HCID 178418361, compound

Product 1

HCID 4585582N-(3-aminopropyl)-pyrrole

Procedure

Similarly prepared according to procedure given in Example 1 is the compound of formula I wherein R1, R2 and R3 represent hydrogen, n represents the integer 1, m represents the integer 3 and Het represents ##STR20## and wherein the cyclohexane and pyrrolidone rings are cis fused, m.p. 78°-79°, starting with 1,3-diaminopropane so as to obtain 3-(1-pyrrolyl)-propylamine which is then condensed with ethyl cyclohexanone-2-acetate.

Workup

  1. customSimilarly prepared

Sources & evidence

ORD record
ord-81e3f59cfbfc47ad920c7746ca27446d
Source dataset
uspto-grants-1990_01
Patent number
US04897399

Reaction notes

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