反应详情

A mixture of 1.33 g (0.01 mol) of rhodanine, 1.80 g (0.01 mol) of 4-chlorobenzalacetone, 20 ml of ethanol and 2 ml of aqueous ammonia was heated under reflux for 4 hours. After cooling, the precipitated crystals were recovered by filtration and washed with methanol to give 0.52 g of the desired 5-(α-methyl-4-chlorocinnamylidene)-4-oxo-2-thioxothiazolidine.

1. temperaturewas heated
2. temperatureunder reflux for 4 hours
3. temperatureAfter cooling
4. filtrationthe precipitated crystals were recovered by filtration
5. washwashed with methanol