Dibromomethane → HCID 14457257, compound

Participants

Reaction Steps

7.36 g (0.021 mol) Triethylammonium N-(2,2-difluoro-1,3-benzodioxol-5-yl)dithiocarbamate was dissolved in 50 ml dimethylformamide. With vigorous stirring, a mixture of 18.25 g (0.105 mol) dibromomethane and 2.12 g (0.021 mol) triethylamine in 20 ml dimethylformamide was added dropwise. It was then stirred for two hours. The reaction mixture was poured into 250 ml ice/water and extracted 3 times with 100 ml diethyl ether. The combined ether phases were dried over magnesium sulphate and concentrated. Purification was then carried out by column chromatography (eluent: hexane/ethyl acetate 4:1).

Provenance & Evidence