1-(3,4-Dimethoxyphenyl)-2,3-bis(ethoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene → 1-(3,4-Dimethoxyphenyl)-2-ethoxycarbonyl-3-methoxycarbonyl-4-hydroxy-6,7,8-trimethoxynaphthalene

HRID 330563Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C:20]3[C:15](=[CH:16][C:17]([O:25][CH3:26])=[C:18]([O:23][CH3:24])[C:19]=3[O:21][CH3:22])[C:14]([OH:27])=[C:13]([C:28]([O:30][CH2:31]C)=[O:29])[C:12]=2[C:33]([O:35][CH2:36][CH3:37])=[O:34])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].C[O-].[Na+]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C:20]3[C:15](=[CH:16][C:17]([O:25][CH3:26])=[C:18]([O:23][CH3:24])[C:19]=3[O:21][CH3:22])[C:14]([OH:27])=[C:13]([C:28]([O:30][CH3:31])=[O:29])[C:12]=2[C:33]([O:35][CH2:36][CH3:37])=[O:34])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

Reactant 2

HCID 105777341-(3,4-Dimethoxyphenyl)-2,3-bis(ethoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene

HCID 10942334Sodium Methoxide

Product 1

HCID 105293921-(3,4-Dimethoxyphenyl)-2-ethoxycarbonyl-3-methoxycarbonyl-4-hydroxy-6,7,8-trimethoxynaphthalene

Procedure

1-(3,4-dimethoxyphenyl)-2,3-bis(ethoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene obtained in Example 10 is treated with a sodium methoxide solution in the same manner as described in Example 28, whereby 1-(3,4-dimethoxyphenyl)-2-ethoxycarbonyl-3-methoxycarbonyl-4-hydroxy-6,7,8-trimethoxynaphthalene is obtained as colorless prisms.

Sources & evidence

ORD record: ord-5ae26fa5b32d47408656217fd7fd6bcd
Source dataset: uspto-grants-1990_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04897418

Reaction notes

Loading…